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bullet WINTER 2010
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UPCOMING EVENTS

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Informex 2010 - Booth 1328
February 16-19
San Francisco, CA


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Chemistry Playbook
March 4, 2010
Boston, MA

 

IN THIS ISSUE

bullet Chemistry Playbook

bullet Coupling Agent T3P

bullet Low Cost Synthesis Services

bullet Large Scale Manufacturing Underway in New Facility

bullet Employee Highlights

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bullet info@c-mlabs.com

bullet 262-251-5044

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Chemistry Playbook

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Are you struggling with managing the linkages between your external suppliers? CML has teamed up with three highly respected companies to provide practical common sense solutions to expedite your drug development process; we call it Chemistry Playbook.

CML is sponsoring a symposium in Boston on March 4th where we will unveil the Chemistry Playbook. Please join us at this event.

Coupling Agent T3P: An interesting non-toxic and economical alternative

Dr. Arian van Eijk, Project Manager, CML Europe 

A lot of interesting chemical entities contain amide moieties. Peptides are the most well-known ones. Peptide chemistry is well developed and these interesting molecules can be even produced in computerized reactor set-ups, where protection, coupling and deprotection is part of the chemical transformations applied.

Low Cost Synthesis Services

CML is introducing a low cost small scale synthesis services initiative. Leveraging the company’s vast experience in chemical synthesis, advanced analytical techniques, and US-based location, CML will provide this expanded service offering starting February 2010.

 
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Large Scale Manufacturing Underway in New Facility

Operators in Isolation Bay

After five full months of operation, CML has successfully produced numerous batches of API and pharma intermediates. All critical systems are running smoothly and CML is gearing up for additional manufacturing programs throughout 2010.

Chong Moua and Richard DeLuna, CML Operators

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CML Employee Spotlight

RICHARD DELUNA - CML Manufacturing Operations

Richard joined CML in June 2009 to support start up and production at the new Large Scale API facility. He has been a tremendous asset to CML and has provided overall leadership to the large scale manufacturing group. Much of the success of startup and initial production in CML’s new facility can be contributed to Richard’s experience, knowledge, foresight, and hard work.

Prior to joining CML, Richard was a production supervisor with Zach System, formerly PPG Industries, in LaPort, TX. He has experience in GMP operations, emergency response, and rescue.

Richard was born in Holland, Michigan, and then moved with his family when he was 5 yrs old to Texas. He currently lives in Mequon, Wisconsin with his wife Dawn, and two boys, Ryan (6) and Matthew (4).

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New Appointments at CML

JAMES KANTER - Director of Business Development

James joined CML as Director of Business Development in January of 2010. His unique combination of drug development expertise and vast network of contacts in the biotech sector make James a real asset to CML. He will be responsible for developing new business opportunities for CML, as well as providing guidance to the organization in strategic alliances and overall CMC management.

James has over 15 years of experience as a process chemist and CMC expert in the biotech and pharmaceutical industry. He has been involved in the development of more than 25 small molecule compounds spanning the areas from late lead optimization through to commercial launch. This includes compounds in the areas of oncology, cardiovascular, CNS, anti-viral, anti-biotic, and pain therapeutics.

He was instrumental in the establishment of several process and pharmaceutical science groups at such companies as Microcide Pharmaceuticals, COR Therapeutics, Millennium (now Takeda) and Exelixis. In addition he has consulted for virtual, small, and mid-sized biotechs with compounds at varying stages of clinical development.

James obtained his undergraduate and graduate degree at the University of Toronto doing work in the area of physical organic chemistry. James has numerous publications and patents spanning the areas of mechanistic, synthetic, and process chemistry.

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